WebI hold strong knowledge and practical expertise in the field of protein aggregation and stabilization of misfolded proteins specifically with biophysical characterization and intracellular studies of neuronal protein α-synuclein. I also hold strong knowledge in neuronal cell biology. Along with it I also have strong practical working experience in … WebNov 8, 2024 · Although OA is a powerful tool available for mechanisms of the neurotoxicity associated with AD, the exact mechanism underlying the activation of microglial cells remains unrevealed. The aim of this study was to determine the effect of both OA and OA-treated neuroblastoma SH-SY5Y cells on microglial HAPI cell viability, activation, and ...
Ramani Soundararajan - Advanced Research Scientist - LinkedIn
WebDetermination of the most suitable novel transfection protocol for the SH-SY5Y cell line with a plasmid designed for the study of oxidative stress and achievement of 20% transfection yield. Conduction of kinetic studies, live-cell imaging studies, MTT assay and flow cytometry analysis in transfected cells to investigate the neuroprotective activity of curcumin and … WebSH-SY5Y cells, the subline of the parental line SK-N-SH cells, are originally established from a bone marrow biopsy of a neuroblastoma patient with sympathetic adrenergic ganglial origin. SH-SY5Y cell line is widely used in laboratory medical scientific research, such as drug development and Parkinson’s Disease research, based on the advantages of its … slow drying wood stain
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WebIn human malignant neuroblastoma SH-SY5Y and SK-N-BE2 cancer cell lines, genistein and retinoid N-(4-hydroxyphenyl) retinamide ... The other five metabolites form as microbial derivatives. Therefore, genistein may trap MGO to prevent hyperglycemia and diabetes. Using a mouse culture model C 2 C1 2 myogenic cell line ... WebProliferative SH-SY5Y cells are seeded and cultured in medium supplemented with 10% FBS for 24 ... Having a good model of microbiome-to-GBA signaling may connect the dots … WebDec 30, 2024 · In addition, compounds with a potential neuroprotective role may be tested on neurotoxicity-induced SH-SY5Y models. The cell line can also be used for testing PD … slow drying epoxy glue