Rnf185
WebSep 9, 2011 · Here we show that human RNF185 is a mitochondrial ubiquitin E3 ligase that regulates selective mitochondrial autophagy in cultured cells. The two C-terminal … WebJan 18, 2024 · RNF185, the first discovered E3 ubiquitin ligase of cGAS, specifically catalyzes K27-linked polyubiquitination to enhance cGAS enzymatic activity and increase …
Rnf185
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WebMar 21, 2024 · RNF185 (Ring Finger Protein 185) is a Protein Coding gene. Diseases associated with RNF185 include Cystic Fibrosis . Among its related pathways are … WebCode used to analyze human CPD-Capture-seq data for the 2024 Selvam et al. paper - CPD-Capture-seq/hayward2024_mutated_tfbs_promoter_simplesort_Capture_driver_BLCAP ...
WebDec 1, 2001 · Protects cells from ER stress-induced apoptosis ( PubMed: 27485036 ). Responsible for the cotranslational ubiquitination and degradation of CFTR in the ERAD … Web– Passionate about designing and executing research projects using gene therapy assay and interdisciplinary research to transform human life. – Experienced in discovering novel genes functional in protein homeostasis and applicable in neurodegenerative disease. – Skilled in implicating cutting-edge biochemistry and microscopy methods …
WebDescription: Homo sapiens derlin 1 (DERL1), transcript variant 1, mRNA. (from RefSeq NM_024295) RefSeq Summary (NM_024295): The protein encoded by this gene is a member of the derlin family. Members of this family participate in the ER-associated degradation response and retrotranslocate misfolded or unfolded proteins from the ER lumen to the … http://www.reactome.org/content/detail/R-HSA-8866856
WebNuclear envelope (NE) and endoplasmic reticulum (ER) collaborate to control a multitude of nuclear and cytoplasmic actions. In this context, the transmembrane protein TMEM147 localizes to both NE and ER, and through direct and indirect interactions
WebSep 23, 2024 · Nuclear envelope (NE) and endoplasmic reticulum (ER) collaborate to control a multitude of nuclear and cytoplasmic actions. In this context, the transmembrane protein TMEM147 localizes to both NE and ER, and through direct and indirect interactions regulates processes as varied as production and transport of multipass membrane proteins, … tol jelupangWebRNF185 has 3,312 functional associations with biological entities spanning 8 categories (molecular profile, organism, chemical, functional term, phrase or reference, disease, phenotype or trait, structural feature, cell line, cell type or tissue, gene, protein or microRNA) extracted from 62 datasets. Click the + buttons to view associations for ... tol hongarijeWebRNF5 and RNF185 ubiquitinate misfolded CFTR. RNF5 and RNF185 ubiquitinate misfolded CFTR as part of the retrotranslocon that targets the receptor for degradation through the ERAD pathway. Both depletion of the E3 ligases by siRNA and expression of a catalytically inactive form of the enzyme strongly inhibits CFTR degradation (El Khouri et al ... tol genap ganjilWebA, Fold-enrichment plots. Graphs depict enrichment vs nominal −log 10 P values (corrected for inflation) in amyotrophic lateral sclerosis (ALS) below the standard genome-wide association study threshold of P < 5 × 10 −8 as a function of significance of association with Parkinson disease (PD), Alzheimer disease (AD), corticobasal degeneration (CBD), … tol jelapangWebRNF185. PROTEIN SUMMARY SECTION OVERVIEW RNA DATA. Amygdala Basal ganglia Thalamus Midbrain Pons Medulla oblongata Hippocampal formation Spinal cord White matter Cerebral cortex Cerebellum Choroid plexus Hypothalamus Retina Thyroid gland Parathyroid gland Adrenal gland Pituitary gland Lung Salivary gland Esophagus Tongue … tol govWeb人转录因子sox-4(sox4)elisa试剂盒 ;英文名称: human sox4 elisa kit ;实验名称: 人转录因子sox-4(sox4)elisa试剂盒 ;实验别名: 人转录因子sox-4(sox4)elisa试剂盒 48t/96t ;规格: 48t/96t 报价 人转录因子sox-4(sox4)elisa试剂盒实验目的:本试剂盒仅供研究使用 ,用于 用于测定血清、血浆及相关液体样本中待测物质 ... tol kastje anwbWebTopologically, RNF185 was a mitochondrial outer membrane protein with the RING domain exposed to the cytosol. El Khouri et al. (2013) reported that RNF185 shares 70% sequence … tol jogja cilacap