Myristicin intoxication

Author: kqfv

August undefined, 2024

WebMar 15, 2024 · Intoxication symptoms after the ingestion of seeds of the nutmeg tree ( Myristica fragrans, Houtt.) have been described in literature for more than 400 years. 1 Since then, numerous cases were reported after accidental, intentional, or suicidal overdosing of the seeds, leading to symptoms such as agitation, nausea, and in severe cases to … Web(PIM 355) Myristica fragrans Houtt. 1. NAME 1.1 Scientific name 1.2 Family 1.3 Common name(s) and synonym(s) 2. SUMMARY 2.1 Main risks and target organs 2.2 Summary of clinical effects 2.3 Diagnosis 2.4 First-aid measures and management principles 2.5 Poisonous parts 2.6 Main toxins 3. CHARACTERISTICS 3.1 Description of the plant

Toxicological evaluation of myristicin - PubMed

WebMyristicin can alter the toxicity of other compounds. For example, myristicin caused a change in the pathway of parathion degradation when fed to rats (Marcus & Lichtenstein, 1982). Myristicin also completely prevented carbon tetrachloride-induced hepatotoxicity in mice (Zhao & O’Brien, 1996). Chronic/Carcinogenicity Studies . ... WebNutmeg comes from the shelled, dried seed. Mace comes from the seed covering. Nutmeg contains chemicals that might affect the central nervous system. Nutmeg might also kill bacteria and fungi ... arancia salata

Toxicity of nutmeg (Myristicin): ... preview & related info Mendeley

WebOct 22, 2024 · Myristicin is the chemical compound in nutmeg that causes nutmeg intoxication. It also occurs naturally in the essential oils present in certain plants, … http://fulbrightsrilanka.com/b6dhc5r/how-long-does-it-take-for-nutmeg-to-kick-in asua xalapa

Metabolic Activation of Myristicin and Its Role in Cellular Toxicity

Introduction - NTP Technical Report on the Toxicity …

WebMar 20, 2014 · There was no other clear cause of death, and postmortem serum myristicin concentration was 4 mg/L. That sounds impressive, but with precious little postmortem data we can’t make much of it. The take home message is that even something as simplistic and innocuous as nutmeg can present dangers. WebAlthough it has been reported that a useful differentiating sign from anticholinergic intoxication such as belladonna alkaloids or atropine poisoning is that myristicin may … asua twiWebMay 1, 2001 · In another case of nutmeg intoxication caused by ingestion of approximately 280-420 mg/mL of nutmeg powder, myristicin blood level was of 2 μg/mL measured 8 h … aranara genshin plush

"WebApr 15, 2001 · An acute nutmeg intoxication causes mostly gastrointestinal symptoms (nausea, abdominal pain and vomiting) as well as mouth dryness and variations of the … " - Myristicin intoxication

Myristicin intoxication

WebM. Smith, in Encyclopedia of Toxicology (Third Edition), 2014 Toxicokinetics. Research on nutmeg and its components peaked in the 1960s. Myristicin is often implicated as the chemical responsible for toxicity, but this remains hypothetical. The essential oil contains 5–15% volatile oils. These divide into monoterpine hydrocarbons (80%), monoterpine … WebMyristicin is a naturally occurring compound found in common herbs and spices, the best-known being nutmeg.It is an insecticide, and has been shown to enhance the effectiveness of other insecticides in combination. Myristicin is also a precursor for substituted amphetamine derivative compounds structurally related to MMDA and MDMA; it was …

Did you know?

WebApr 12, 2024 · A 1997 study found data to suggest that myristicin can alter the toxicity and/ or metabolic pathway of some compounds. 1997年の研究では、ミリスチシンはいくつかの化合物の毒性と代謝経路を変えるというデータが得られた。 WebMyristicin C11H12O3 CID 4276 - structure, chemical names, physical and chemical properties, classification, patents, literature, biological activities, safety/hazards/toxicity information, supplier lists, and more. National Institutes of Health. National Library of Medicine. National Center for Biotechnology Information. PubChem ...

WebAlthough myristicin is believed to be the active component of nutmeg oil, there is still some ambiguity as to whether its relative potency can fully explain nutmeg intoxication. Therefore, the reports summarized herein … WebThe most sensitive measure of myristicin toxicity in female mice was an increase in absolute and relative liver weight (LOEL = 10 mg/kg). No-observed-effect levels were 10 mg/kg for male rats and 30 mg/kg for male mice, but none was reached for female rats or mice. National Toxicology Program (NTP). 2024.

WebApr 15, 2001 · An acute nutmeg intoxication causes mostly gastrointestinal symptoms (nausea, abdominal pain and vomiting) as well as mouth dryness and variations of the pupil width (mydriasis, however also miosis). Furthermore, typical clinical features of the central nervous system and cardiovascular system will develop. WebJul 5, 2024 · Moreover, the current knowledge on the toxicity of myristicin and elemicin in comparison to their structurally related and well-characterized derivatives safrole and methyleugenol, especially with respect to their genotoxic and carcinogenic potential, is …

WebApr 17, 2024 · Abstract. Myristicin is widely distributed in spices and medicinal plants. The aim of this study was to explore the role of metabolic activation of myristicin in its potential toxicity through a metabolomic approach. The myristicin- N-acetylcysteine adduct was identified by comparing the metabolic maps of myristicin and 1'-hydroxymyristicin.

WebAt higher dosage of myristicin death may occur. Additionally, Myristicin poisoning can lead to many health problems that related to brain problem. Those symptoms usually occur 3 … asua540badm888tWebApr 15, 2001 · Even where higher doses (20-80 g of powder) had been ingested, a life-threatening situation was never observed. In one of these cases, a myristicin blood level … asua wineWebAug 15, 2012 · Myristicin poisoning can lead to many health problems such as convulsions, delirium, blurred vision, palpitations, nausea, dehydration, general body pain, and others . … arandela tartaruga blindadaWebJan 23, 2014 · Nutmeg is a commonly consumed spice. The toxic effects of nutmeg have been purported to be due mainly to myristicin oil. Prior poison center series of nutmeg exposures show very few unintentional exposures of nutmeg to children younger than 13. Case series from these centers did not record drug exposures combined with nutmeg. … asua vg27aWebMyristicin C11H12O3 CID 4276 - structure, chemical names, physical and chemical properties, classification, patents, literature, biological activities, safety/hazards/toxicity … arandela hadarWebNov 21, 2024 · The cytotoxic and apoptotic effects of myristicin have been explored. Cell viability was reduced by exposure to myristicin in a dose- and time-dependent manner. 20 … aranduwebWeb[16] [27] Myristicin—a monoamine oxidase inhibitor and psychoactive substance [2] [16] —can cause convulsions, palpitations, nausea, eventual dehydration, and generalized body … asua vg245h