WebHere we compared the ability of gamma-irradiation- and mitomycin C-treated feeder cells to support the expansion of normal human B lymphocytes. The results indicate that expansion of B cells during a long-term culture was 100 times more potent using gamma-irradiated feeder cells compared to mitomycin C-treated cells. WebMitomycin selectively inhibits the synthesis of deoxyribonucleic acid (DNA). The guanine and cytosine content correlates with the degree of mitomycin-induced cross-linking. At high concentrations of the drug, cellular RNA and protein synthesis are also suppressed. In humans, mitomycin is rapidly cleared from the serum after intravenous ...
Mitomycin C induction of bacteriophages from - Oxford Academic
WebProduktbeschreibung: Mitomycin C Cat No. : 226940000; 226940020 Synonyme Ametycine. Summenformel C15 H18 N4 O5 1.2. Relevante identifizierte Verwendungen … Web12 apr. 2024 · A human transcriptome array on ERα-positive breast cancer continuum of risk identified Secreted Frizzled-Related Protein 1 (SFRP1) as decreased during breast cancer progression. In addition, SFRP1 was inversely associated with breast tissue age-related lobular involution, and differentially regulated in women with regard to their parity status … clash royale deck generator
Mitomycin - StatPearls - NCBI Bookshelf
Web1 jul. 2024 · Colicin Ia was purified from E. coli cells induced with mitomycin C. • The samples contained the protein Dps as an impurity. • The Dps structure strongly … Web1 apr. 1997 · Mitomycin C [aziridine(2′,3′:3,4) pyrrole (1, 2-α) indol-4, 7-dione-6-amino-1,1a,2,8,8a,8b-exahydro-8-(hydroxymethyl) 8a-metoxy-5-methylcarbamate] (MMC) is an antimicrobial and anticancer agent that was isolated in 1958 from the fermentation fluid culture medium of Streptomyces caespitosus (). 1 Since then, several clinical trials … WebS.E. Gad, in Encyclopedia of Toxicology (Third Edition), 2014 Uses. Mitomycin C is used as an antineoplastic agent and for slowing of fibroblast formation in open-angle glaucoma. Recently, mitomycin C has been used to induce tumor responses in patients with many types of cancer. For example, mitomycin C has been used in combination with other … clash royale dark prince