WebNov 12, 2024 · The PLASMIC and French TTP scores have reduced sensitivity at age ≥ 60 years and are less reliable in identifying TTP in older patients. A high index of suspicion and availability of rapid ADAMTS13 assays is required to correctly diagnose all patients with TTP. Full text links . WebBackground: Thrombotic thrombocytopenic purpura (TTP) is a life-threatening disorder characterized by thrombocytopenia, microangiopathic hemolysis, and ischemic organ …
Reduced sensitivity of PLASMIC and French Scores for the
WebApr 13, 2024 · Thrombotic thrombocytopenic purpura (TTP) is a rare life-threatening thrombotic microangiopathy that is characterized by the deficiency of the ADAMTS13 enzyme. ... In fact, the well-validated PLASMIC score was found to be less sensitive in the elderly population. 3 Older patients are less likely to exhibit significant cytopenias, more … WebNov 12, 2024 · We calculated the sensitivity and specificity of the PLASMIC and French TTP scores in patients enrolled in the Johns Hopkins thrombotic microangiopathy (TMA) … tiverton youth club
Comparison of Clinical Scoring Systems in the Management …
WebApr 1, 2024 · The French score, 27 was based on a cross-sectional analysis of the French TMA reference center records from 2000 to 2007. ... Among the scores developed for … WebNov 10, 2024 · In addition, several required parameters were not included in the case reports. Despite those significant limitations, at least 4/19 (21%) patients still had a score of 0 as per the French criteria and at least 11/19 (58%) had a PLASMIC score of ≤5 . No published case documented ADAMTS13 activity of <10%; in 16 (84%) there was no … WebNov 12, 2024 · Thrombotic thrombocytopenic purpura (TTP) is a life-threatening disorder characterized by thrombocytopenia, microangiopathic hemolysis, and ischemic organ … tiverton youth soccer ri