WebResults: The DHE protocol was shown to decrease headache frequency, severity, headache medication use, and absences from work both at three months and the time of interview. Conclusion: This study has the largest patient base and the longest follow-up period for the use of DHE for CDH. The results confirm that the DHE protocol is helpful … WebRaskin developed the original repetitive dose IV DHE protocol to treat refractory migraine in 1986. This became the foundation for inpatient and in-clinic treatments administered over a number of days. ... with most patients achieving improvement in 2 to 3 days. 15 Other studies also support the effectiveness of IV DHE in reducing headache ...
Migraine Headache Clinical Pathway — Inpatient
WebDec 7, 2024 · Table 12.17 Alternatives and variations to Raskin DHE protocol. 1. Continuous IV DHE: once the dose titration has been completed, wait several hours and start infusing that amount by continuous IV infusion over an hour period. This will require a volumetric infusion pump and inpatient status (a) Continue this infusion until headache-free WebWe reviewed data on 171 patients with refractory headache treated by continuous intravenous dihydroergotamine mesylate (i.v. DHE 45) and repetitive i.v. DHE and compared the efficacy of continuous i.v. DHE to repetitive i.v. DHE. One hundred (58.5%) patients had refractory chronic daily headache. Seventy-one (42%) had drug rebound headache. csl plasma inc near me
Inpatient Treatment of Status Migraine With Dihydroergotamine in ...
WebBackground: Dihydroergotamine (DHE) has been used for decades to treat migraine, but is currently contraindicated in patients with hemiplegic migraine and basilar-type migraine (BTM). Objective: To assess the safety of DHE in patients with symptoms of BTM that do not meet criteria for BTM. Methods: Retrospective analysis of patients admitted to an … WebCluster headache. Of 38 patients admitted for DHE, 26 were men with a mean of 27 attacks per week before treatment. Four had episodic cluster headache and the remainder had chronic cluster headache.1 Each patient had medically refractory cluster head-ache.23 Six of the cohort had experienced migraine at other times, and this was not the ... WebStatistical Analysis Plan INP104 (POD-DHE) Clinical Study Protocol INP104-301Impel NeuroPharma Inc FINAL v2.0 CONFIDENTIAL 1 ... POD-DHE] in Patients with Migraine Headache INVESTIGATIONAL PRODUCT INP104 or POD-DHE PROTOCOL NUMBER INP104-301 PROTOCOL VERSION, DATE Amendment 03 (A03) – FINAL v4.0, 26 … csl plasma hr