Cimetidine and theophylline drug interaction

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WebInfluences of cimetidine dose and age on the cimetidine-theophylline interaction were evaluated. Group Y consisted of nine young adults, aged 22–35 years, and Group O of nine elderly adults, aged 60–74 years. Each subject completed three study phases in this randomized crossover study. During Phase A, oral dosing of 5 mg/kg theophylline was ... WebDrug Interactions Cytochrome P450 Inhibition Strong and Moderate Inhibitors of CYP3A4 or CYP2D6 The effects of ketoconazole (a strong inhibitor of CYP3A4) at 400 mg once daily for 5 days on the pharmacokinetics of a single tamsulosin hydrochloride capsule 0.4 mg dose was investigated in 24 healthy volunteers (age range 23 to 47 years).

Drugs interact theophylline I - UpToDate

WebInfluences of cimetidine dose and age on the cimetidine-theophylline interaction were evaluated. Group Y consisted of nine young adults, aged 22–35 years, and Group … WebCimetidine belongs to a class of drugs commonly called H2 blockers. It works by reducing the amount of acid in your stomach. ... theophylline, among others. Since cimetidine reduces the amount of ... lee may brachers

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WebDec 13, 2012 · Clinically important interactions are predominantly manifested in those drugs which have a narrow therapeutic index (e.g. Phenytoin, warfarin, theophylline). The interaction leads to higher steady-state blood concentrations and hence increases the incidence of side effects and toxicity. Adverse effects of such interactions can be … WebPhenytoin increases theophylline clearance by increasing microsomal enzyme activity: Serum theophylline and phenytoin concentrations decrease about 40 percent: … WebMar 22, 2024 · Drug-Drug Interactions: Theophylline interacts with a wide variety of drugs. The interaction may be pharmacodynamic, i.e. alterations in the therapeutic response to theophylline or another drug or occurrence of adverse effects without a change in serum theophylline concentration. ... Cimetidine. Decreases theophylline … how to figure cap rate for investment

Cimetidine: Uses, Interactions, Mechanism of Action

Cimetidine: MedlinePlus Drug Information

WebMay 8, 2024 · Warfarin's hepatic metabolism and protein binding are the most common mechanisms for the occurrence of drug-drug interactions. Warfarin is metabolized via the cytochrome P450 system by CYP 2C9, 1A2, and 3A4. It is a racemic mixture, with the S-enantiomer being 2.7 to 3.8 times more potent than the R-enantiomer. WebThere are 7 disease interactions with theophylline which include: PUD renal dysfunction seizure disorders GERD hemodialysis reduced clearance tachyarrhythmias Report … how to figure capital gains tax on stockWebAug 25, 2024 · Severe interactions of cimetidine include: astemizole; cisapride; dofetilide; eliglustat; lomitapide; pimozide; terfenadine; Cimetidine has serious interactions with at … how to figure capital gains tax

"WebThe tablet drug load (10.5–19.5 mg) of theophylline (2.25 mg increments) and cimetidine (3 mg increments) could easily be differentiated using univariate analyses. " - Cimetidine and theophylline drug interaction

Cimetidine and theophylline drug interaction

WebThe effects of cimetidine (1 g/day) on theophylline disposition and metabolism were examined in smokers and non-smokers for single dose intravenous and chronic oral administration of theophylline. In the intravenous study the effect of cimetidine on plasma theophylline clearance was more marked in smokers (22.7% reduction) than in non … WebThis study compared the effects of diet and cimetidine on theophylline metabolism and examined interactions between these effects. Twelve men received a high-protein diet for 15 days and at another time a high-carbohydrate diet also for 15 days. Cimetidine, 800 mg daily at bedtime, was administered on days 10 through 15 of each dietary period.

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WebBlood in your stools (black or tarry stools) or if you have blood in your vomit. Kidney disease. Liver disease. Pain or trouble trying to swallow food. An unusual or allergic reaction to … WebAfter intravenous administration of cimetidine, the majority of the parent drug (58-77%) is eliminated unchanged in the urine. 2,7 Cimetidine’s primary metabolite is cimetidine sulfoxide and represents an estimated …

WebFeb 1, 1983 · The effects of cimetidine on the pharmacokinetics of theophylline were studied in seven healthy subjects at steady state after oral dosing. Aminophylline (200 mg) was administered every six hours for three days (AX then aminophylline (200 mg) and cimetidine (300 mg) were administered every six hours for seven days (A-CX Multiple …

WebSearch for drug interactions with our API. Drug Allergy. ... non-bronchodilator prophylactic effects). Mechanism of action. Theophylline relaxes the smooth muscle of the bronchial airways and pulmonary … WebC or lactation Drug to drug interaction ... of hallucinations or psychosis Thyrotoxicosis Peptic ulcer Pregnancy category C Ropinirole Pramipexole Drug to drug Interactions Cimetidine, ... with magnesium and aluminum Decreased effectiveness of bisphosphonates Aspirin Increase risk of GI bleeding Theophylline ...

WebApr 22, 2024 · Adult dosage (ages 18–59 years) The usual starting dose is 300–400 mg per day. After 3 days, your dose may be increased to 400–600 mg per day if you don’t have any side effects. After 3 ...

WebMar 1, 1983 · The effects of cimetidine on the pharmacokinetics of theophylline were studied in seven healthy subjects at steady state after oral dosing. Aminophylline (200 mg) was administered every six hours ... lee mayberry bucksWebCimetidine-theophylline interaction: effects of age and cimetidine dose. Influences of cimetidine dose and age on the cimetidine-theophylline interaction were evaluated. … lee mayberry statsWebSome side effects can be serious. The following symptoms are uncommon, but if you experience any of them, call your doctor immediately: confusion; excitement; depression; … lee may baseball statsWebTheophylline comes as an extended-release (long-acting) tablet, extended-release capsule, and a solution (liquid) to take by mouth. It usually is taken every 6, 8, 12, or 24 hours. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. how to figure cap rate in real estateWeb[Interaction between theophylline and cimetidine] [Interaction between theophylline and cimetidine] [Interaction between theophylline and cimetidine] Recenti Prog Med. … lee.ma.us. town clerkWebTheophylline is used to treat lung diseases such as asthma and COPD ( bronchitis, emphysema ). It must be used regularly to prevent wheezing and shortness of breath. This medication belongs to a ... lee mayberry wifeWebAug 25, 2024 · Cimetidine is a prescription medication used as an acid reducer. Cimetidine relieves heartburn associated with acid indigestion and sour stomach. Cimetidine also prevents heartburn associated with acid indigestion and sour stomach brought on by eating or drinking certain foods and beverages. Cimetidine is available under the following … how to figure cap rate on commercial building